Posts tagged Nature
In mice and one person, scientists were able to reproduce the altered state often associated with ketamine by inducing certain brain cells to fire together in a slow-rhythmic fashion. “There was a rhythm that appeared and it was an oscillation that appeared only when the patient was dissociating,” says Dr. Karl Deisseroth, a psychiatrist and neuroscientist at Stanford University. https://sci-hub.tw/10.1038/s41586-020-2731-9
(via https://www.npr.org/sections/health-shots/2020/09/16/913565163/scientists-discover-way-to-induce-altered-state-of-mind-without-drugs?t=1600326978763)
“My message to you is this: pretend that you have free will. It’s essential that you behave as if your decisions matter, even though you know that they don’t. The reality isn’t important: what’s important is your belief, and believing the lie is the only way to avoid a waking coma. Civilization now depends on self-deception. Perhaps it always has.”
–Ted Chiang
During the Ice Age, Earth’s northern reaches were covered by chilly, arid grasslands roamed by mammoths, woolly rhinoceros and long-horned bison. That ecosystem, known by palaeontologists as the mammoth steppe, vanished about 13,000 years ago. It has no modern counterpart. Yet one of its plants has reportedly been resurrected by a team of scientists who tapped a treasure trove of fruits and seeds, buried some 30,000 years ago by ground squirrels and preserved in the permafrost (S. Yashina et al. Proc. Natl Acad. Sci. USA http://dx.doi.org/10.1073/pnas.1118386109; 2012). The plant would be by far the most ancient ever revived; the previous record holder was a date palm grown from seeds roughly 2,000 years old.
via http://www.nature.com/news/wild-flower-blooms-again-after–30–000-years-on-ice–1.10069
We humans are changing. We have become so intertwined with what we have created that we are no longer separate from it. We have outgrown the distinction between the natural and the artificial. We are what we make. We are our thoughts, whether they are created by our neurons, by our electronically augmented minds, by our technologically mediated social interactions, or by our machines themselves. We are our bodies, whether they are born in womb or test tube, our genes inherited or designed, organs augmented, repaired, transplanted, or manufactured. Our prosthetic enhancements are as simple as contact lenses and tattoos and as complex as robotic limbs and search engines. They are both functional and aesthetic. We are our perceptions, whether they are through our eyes and ears or our sensory-fused hyper-spectral sensors, processed as much by computers as by our own cortex. We are our institutions, cooperating super-organisms, entangled amalgams of people and machines with super-human intelligence, processing, sensing, deciding, acting. Our home planet is inhabited by both engineered organisms and evolved machines. Our very atmosphere is the emergent creation of forests, farms and factories. Empowered by the tools of the Enlightenment, connected by networked flows of freight and fuel and finance, by information and ideas, we are becoming something new. We are at the dawn of the Age of Entanglement.
via http://jods.mitpress.mit.edu/pub/enlightenment-to-entanglement
‘Peer review’ was a term borrowed from the procedures that government agencies used to decide who would receive financial support for scientific and medical research. When 'referee systems’ turned into 'peer review’, the process became a mighty public symbol of the claim that these powerful and expensive investigators of the natural world had procedures for regulating themselves and for producing consensus, even though some observers quietly wondered whether scientific referees were up to this grand calling. Current attempts to reimagine peer review rightly debate the psychology of bias, the problem of objectivity, and the ability to gauge reliability and importance, but they rarely consider the multilayered history of this institution. Peer review did not develop simply out of scientists’ need to trust one another’s research. It was also a response to political demands for public accountability. To understand that other practices of scientific judgement were once in place ought to be a part of any responsible attempt to chart a future path. The imagined functions of this institution are in flux, but they were never as fixed as many believe.
via http://www.nature.com/news/peer-review-troubled-from-the-start–1.19763?WT.mc_id=SFB_NNEWS_1508_RHBox
To investigate the molecular bases of cephalopod brain and body innovations, we sequenced the genome and multiple transcriptomes of the California two-spot octopus, Octopus bimaculoides. We found no evidence for hypothesized whole-genome duplications in the octopus lineage. The core developmental and neuronal gene repertoire of the octopus is broadly similar to that found across invertebrate bilaterians, except for massive expansions in two gene families previously thought to be uniquely enlarged in vertebrates: the protocadherins, which regulate neuronal development, and the C2H2 superfamily of zinc-finger transcription factors.
http://www.nature.com/nature/journal/v524/n7564/full/nature14668.html