Researchers use music and LSD to understand how we attribute meaning.

Attribution of meaning and personal relevance is important for our everyday lives. In psychiatric disorders, the attribution of meaning is often altered, and the mechanisms causing this were unknown. LSD has also been shown to alter the attribution of meaning and personal relevance to the environment and our sense of self. However, the exact mechanism and brain structures had not been investigated yet. Therefore, LSD offered a unique opportunity to investigate these phenomena.

via https://www.researchgate.net/blog/post/lsd-unlocks-how-our-brains-impart-meaningfulness